MIT’s Abdul Latif Jameel Water and Food Systems Lab (J-WAFS) has transformed the landscape of water and food research at MIT, driving faculty engagement and catalyzing new research and innovation in these critical areas. With philanthropic, corporate, and government support, J-WAFS’ strategic approach spans the entire research life cycle, from support for early-stage research to commercialization grants for more advanced projects.
Over the past decade, J-WAFS has invested approximately $25 million in direct research funding to support MIT faculty pursuing transformative research with the potential for significant impact. “Since awarding our first cohort of seed grants in 2015, it’s remarkable to look back and see that over 10 percent of the MIT faculty have benefited from J-WAFS funding,” observes J-WAFS Executive Director Renee J. Robins ’83. “Many of these professors hadn’t worked on water or food challenges before their first J-WAFS grant.”
By fostering interdisciplinary collaborations and supporting high-risk, high-reward projects, J-WAFS has amplified the capacity of MIT faculty to pursue groundbreaking research that addresses some of the world’s most pressing challenges facing our water and food systems.
Drawing MIT faculty to water and food research
J-WAFS open calls for proposals enable faculty to explore bold ideas and develop impactful approaches to tackling critical water and food system challenges. Professor Patrick Doyle’s work in water purification exemplifies this impact. “Without J-WAFS, I would have never ventured into the field of water purification,” Doyle reflects. While previously focused on pharmaceutical manufacturing and drug delivery, exposure to J-WAFS-funded peers led him to apply his expertise in soft materials to water purification. “Both the funding and the J-WAFS community led me to be deeply engaged in understanding some of the key challenges in water purification and water security,” he explains.
Similarly, Professor Otto Cordero of the Department of Civil and Environmental Engineering (CEE) leveraged J-WAFS funding to pivot his research into aquaculture. Cordero explains that his first J-WAFS seed grant “has been extremely influential for my lab because it allowed me to take a step in a new direction, with no preliminary data in hand.” Cordero’s expertise is in microbial communities. He was previous unfamiliar with aquaculture, but he saw the relevance of microbial communities the health of farmed aquatic organisms.
Supporting early-career faculty
New assistant professors at MIT have particularly benefited from J-WAFS funding and support. J-WAFS has played a transformative role in shaping the careers and research trajectories of many new faculty members by encouraging them to explore novel research areas, and in many instances providing their first MIT research grant.
Professor Ariel Furst reflects on how pivotal J-WAFS’ investment has been in advancing her research. “This was one of the first grants I received after starting at MIT, and it has truly shaped the development of my group’s research program,” Furst explains. With J-WAFS’ backing, her lab has achieved breakthroughs in chemical detection and remediation technologies for water. “The support of J-WAFS has enabled us to develop the platform funded through this work beyond the initial applications to the general detection of environmental contaminants and degradation of those contaminants,” she elaborates.
Karthish Manthiram, now a professor of chemical engineering and chemistry at Caltech, explains how J-WAFS’ early investment enabled him and other young faculty to pursue ambitious ideas. “J-WAFS took a big risk on us,” Manthiram reflects. His research on breaking the nitrogen triple bond to make ammonia for fertilizer was initially met with skepticism. However, J-WAFS’ seed funding allowed his lab to lay the groundwork for breakthroughs that later attracted significant National Science Foundation (NSF) support. “That early funding from J-WAFS has been pivotal to our long-term success,” he notes.
These stories underscore the broad impact of J-WAFS’ support for early-career faculty, and its commitment to empowering them to address critical global challenges and innovate boldly.
Fueling follow-on funding
J-WAFS seed grants enable faculty to explore nascent research areas, but external funding for continued work is usually necessary to achieve the full potential of these novel ideas. “It’s often hard to get funding for early stage or out-of-the-box ideas,” notes J-WAFS Director Professor John H. Lienhard V. “My hope, when I founded J-WAFS in 2014, was that seed grants would allow PIs [principal investigators] to prove out novel ideas so that they would be attractive for follow-on funding. And after 10 years, J-WAFS-funded research projects have brought more than $21 million in subsequent awards to MIT.”
Professor Retsef Levi led a seed study on how agricultural supply chains affect food safety, with a team of faculty spanning the MIT schools Engineering and Science as well as the MIT Sloan School of Management. The team parlayed their seed grant research into a multi-million-dollar follow-on initiative. Levi reflects, “The J-WAFS seed funding allowed us to establish the initial credibility of our team, which was key to our success in obtaining large funding from several other agencies.”
Dave Des Marais was an assistant professor in the Department of CEE when he received his first J-WAFS seed grant. The funding supported his research on how plant growth and physiology are controlled by genes and interact with the environment. The seed grant helped launch his lab’s work addressing enhancing climate change resilience in agricultural systems. The work led to his Faculty Early Career Development (CAREER) Award from the NSF, a prestigious honor for junior faculty members. Now an associate professor, Des Marais’ ongoing project to further investigate the mechanisms and consequences of genomic and environmental interactions is supported by the five-year, $1,490,000 NSF grant. “J-WAFS providing essential funding to get my new research underway,” comments Des Marais.
Stimulating interdisciplinary collaboration
Des Marais’ seed grant was also key to developing new collaborations. He explains, “the J-WAFS grant supported me to develop a collaboration with Professor Caroline Uhler in EECS/IDSS [the Department of Electrical Engineering and Computer Science/Institute for Data, Systems, and Society] that really shaped how I think about framing and testing hypotheses. One of the best things about J-WAFS is facilitating unexpected connections among MIT faculty with diverse yet complementary skill sets.”
Professors A. John Hart of the Department of Mechanical Engineering and Benedetto Marelli of CEE also launched a new interdisciplinary collaboration with J-WAFS funding. They partnered to join expertise in biomaterials, microfabrication, and manufacturing, to create printed silk-based colorimetric sensors that detect food spoilage. “The J-WAFS Seed Grant provided a unique opportunity for multidisciplinary collaboration,” Hart notes.
Professors Stephen Graves in the MIT Sloan School of Management and Bishwapriya Sanyal in the Department of Urban Studies and Planning (DUSP) partnered to pursue new research on agricultural supply chains. With field work in Senegal, their J-WAFS-supported project brought together international development specialists and operations management experts to study how small firms and government agencies influence access to and uptake of irrigation technology by poorer farmers. “We used J-WAFS to spur a collaboration that would have been improbable without this grant,” they explain. Being part of the J-WAFS community also introduced them to researchers in Professor Amos Winter’s lab in the Department of Mechanical Engineering working on irrigation technologies for low-resource settings. DUSP doctoral candidate Mark Brennan notes, “We got to share our understanding of how irrigation markets and irrigation supply chains work in developing economies, and then we got to contrast that with their understanding of how irrigation system models work.”
Timothy Swager, professor of chemistry, and Rohit Karnik, professor of mechanical engineering and J-WAFS associate director, collaborated on a sponsored research project supported by Xylem, Inc. through the J-WAFS Research Affiliate program. The cross-disciplinary research, which targeted the development of ultra-sensitive sensors for toxic PFAS chemicals, was conceived following a series of workshops hosted by J-WAFS. Swager and Karnik were two of the participants, and their involvement led to the collaborative proposal that Xylem funded. “J-WAFS funding allowed us to combine Swager lab’s expertise in sensing with my lab’s expertise in microfluidics to develop a cartridge for field-portable detection of PFAS,” says Karnik. “J-WAFS has enriched my research program in so many ways,” adds Swager, who is now working to commercialize the technology.
Driving global collaboration and impact
J-WAFS has also helped MIT faculty establish and advance international collaboration and impactful global research. By funding and supporting projects that connect MIT researchers with international partners, J-WAFS has not only advanced technological solutions, but also strengthened cross-cultural understanding and engagement.
Professor Matthew Shoulders leads the inaugural J-WAFS Grand Challenge project. In response to the first J-WAFS call for “Grand Challenge” proposals, Shoulders assembled an interdisciplinary team based at MIT to enhance and provide climate resilience to agriculture by improving the most inefficient aspect of photosynthesis, the notoriously-inefficient carbon dioxide-fixing plant enzyme RuBisCO. J-WAFS funded this high-risk/high-reward project following a competitive process that engaged external reviewers through a several rounds of iterative proposal development. The technical feedback to the team led them to researchers with complementary expertise from the Australian National University. “Our collaborative team of biochemists and synthetic biologists, computational biologists, and chemists is deeply integrated with plant biologists and field trial experts, yielding a robust feedback loop for enzyme engineering,” Shoulders says. “Together, this team will be able to make a concerted effort using the most modern, state-of-the-art techniques to engineer crop RuBisCO with an eye to helping make meaningful gains in securing a stable crop supply, hopefully with accompanying improvements in both food and water security.”
Professor Leon Glicksman and Research Engineer Eric Verploegen’s team designed a low-cost cooling chamber to preserve fruits and vegetables harvested by smallholder farmers with no access to cold chain storage. J-WAFS’ guidance motivated the team to prioritize practical considerations informed by local collaborators, ensuring market competitiveness. “As our new idea for a forced-air evaporative cooling chamber was taking shape, we continually checked that our solution was evolving in a direction that would be competitive in terms of cost, performance, and usability to existing commercial alternatives,” explains Verploegen. Following the team’s initial seed grant, the team secured a J-WAFS Solutions commercialization grant, which Verploegen say “further motivated us to establish partnerships with local organizations capable of commercializing the technology earlier in the project than we might have done otherwise.” The team has since shared an open-source design as part of its commercialization strategy to maximize accessibility and impact.
Bringing corporate sponsored research opportunities to MIT faculty
J-WAFS also plays a role in driving private partnerships, enabling collaborations that bridge industry and academia. Through its Research Affiliate Program, for example, J-WAFS provides opportunities for faculty to collaborate with industry on sponsored research, helping to convert scientific discoveries into licensable intellectual property (IP) that companies can turn into commercial products and services.
J-WAFS introduced professor of mechanical engineering Alex Slocum to a challenge presented by its research affiliate company, Xylem: how to design a more energy-efficient pump for fluctuating flows. With centrifugal pumps consuming an estimated 6 percent of U.S. electricity annually, Slocum and his then-graduate student Hilary Johnson SM ’18, PhD ’22 developed an innovative variable volute mechanism that reduces energy usage. “Xylem envisions this as the first in a new category of adaptive pump geometry,” comments Johnson. The research produced a pump prototype and related IP that Xylem is working on commercializing. Johnson notes that these outcomes “would not have been possible without J-WAFS support and facilitation of the Xylem industry partnership.” Slocum adds, “J-WAFS enabled Hilary to begin her work on pumps, and Xylem sponsored the research to bring her to this point … where she has an opportunity to do far more than the original project called for.”
Swager speaks highly of the impact of corporate research sponsorship through J-WAFS on his research and technology translation efforts. His PFAS project with Karnik described above was also supported by Xylem. “Xylem was an excellent sponsor of our research. Their engagement and feedback were instrumental in advancing our PFAS detection technology, now on the path to commercialization,” Swager says.
Looking forward
What J-WAFS has accomplished is more than a collection of research projects; a decade of impact demonstrates how J-WAFS’ approach has been transformative for many MIT faculty members. As Professor Mathias Kolle puts it, his engagement with J-WAFS “had a significant influence on how we think about our research and its broader impacts.” He adds that it “opened my eyes to the challenges in the field of water and food systems and the many different creative ideas that are explored by MIT.”
This thriving ecosystem of innovation, collaboration, and academic growth around water and food research has not only helped faculty build interdisciplinary and international partnerships, but has also led to the commercialization of transformative technologies with real-world applications. C. Cem Taşan, the POSCO Associate Professor of Metallurgy who is leading a J-WAFS Solutions commercialization team that is about to launch a startup company, sums it up by noting, “Without J-WAFS, we wouldn’t be here at all.”
As J-WAFS looks to the future, its continued commitment — supported by the generosity of its donors and partners — builds on a decade of success enabling MIT faculty to advance water and food research that addresses some of the world’s most pressing challenges.